Monday, January 26, 2009

AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE






The organs which are shown here belong to a man in his fifities who died suddenly after an intense bout of headache. He had high blood pressure which he did not mind at controlling carefully. The kidneys were symmetrically enlarged and multicystic, each one weighing over 1000g. Cysts were also found in the liver and in the pancreas, the former more widely involved. The subarachnoid space and leptomeninges were full of blood. Thus, the cause of death was presumably massive subarachnoid hemorrhage.

1 comment:

Fernanda said...

Hi doc Luciano, very very interesting case. Is it from SVO? According to Robbins, massive subarachnoid hemorrhage accounts for 4 to 10% of deaths, and these patients usually have aneurysms in the circle of Willis due to altered expression of polycystin in vascular smooth muscle.
Great idea of creating this blog!!
Fernanda Melo (UFC)